IDEXX Diagnostic Challenge: Why is Angel Anemic?
IDEXX Diagnostic Challenge: Why is Angel Anemic? History: Angel, a 9-month-old spayed female Yorkshire Terrier, was referred for evaluation of anemia that developed the day after surgery to remove a metallic button from her stomach. Laboratory Results: A CBC, Chemistry profile, Spec cPL, and urinalysis were submitted to IDEXX for analysis. On the CBC, the sample was grossly hemolyzed, and there was severe, macrocytic, hypochromic, regenerative anemia with a hematocrit of 16.3% (reference interval, 37-55%)…
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IL-31 for Canine Atopic Dermatitis
Zoetis has been granted conditional release of their Canine Atopic Dermatitis Immunotherapeutic monoclonal antibody against IL-31. This injection has been developed for managing pruritus in dogs by binding their IL-31 with a monoclonal antibody. Like Apoquel (oclacitinib), it has the potential to reduce pruritus within 24 to 48 hours with a single subcutaneous injection lasting up to 3 to 6 weeks depending on the dose and responsiveness of the patient. Approximately 90% of patients respond…
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New Topical Therapy for Feline Eosinophilic Keratoconjunctivitis
Feline eosinophilic keratoconjunctivitis is an inflammatory condition that affects the cornea and/or conjunctiva. It is characterized by mucopurulent discharge and pink/white raised plaques on the cornea or conjunctiva. Eosinophils are often noted on corneal cytology which confirms the diagnosis. Treatment of eosinophilic keratoconjunctivitis Treatment of eosinophilic keratoconjunctivitis is topical anti-inflammatory therapy with either cyclosporine, tacrolimus, or prednisolone acetate combined with a topical antiviral or oral therapy with megestrol acetate. Side effects of topical therapy include…
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